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The microINR Chip is a disposable plastic test strip, that encloses two microcapillary channels, of extremely simple construction and fully passive (i.e. no built-in sensors, nor electrodes, nor external pumping).


Microfluidics Chips

The INR determination is achieved through sample flow monitoring along the microcapillary channels of the Chip, following the activation of the coagulation cascade. The current IVD test mimics the conditions of “in vivo” hemostasis, also referred as “ex vivo”


Entry Channel

The blood sample introduction is performed through the entry channel, where the sample flows by capillary action


Reaction Chambers

After blood sample application on the Chip, the coagulation cascade is activated by a microdispensed amount of recombinant thromboplastin reagent


Microcapillary channels

INR determination is performed through capillary blood flow monitoring along microfluidic channels.


Control Channel

Parallel control channel to check reagent integrity


Measurement Channel

When clotting, blood undergoes a change on the behavior and, thus, a sudden flow rate decay, which is detected by an embedded Machine Vision System (MVS)



The measured prothrombin time is converted into INR using lot-specific calibration parameters microprinted on the Chip surface (Datamatrix)


Safety and reliability

On-board quality control

Chips individually packed

Small sample volume (3ul)

Solid strip


Chip Specifications

  • High sensitivity human recombinant thromboplastin
  • Real control assay in parallel channel
  • Chip expiry and calibration parameters coded and integrated into the Chip
  • Individually packed
  • Storage at room temperature (2-25ºC / 36-77ºF)
  • 15 Months shelf life


System specifications

  • 3 μL sample volume required
  • Measurement range: 0.8 – 4.5 INR
  • System ISI: Approx. 1
  • Multilevel on-board QC performed in each assay

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